hekarl

ASSOCIATE PROFESSOR DR. MOHAMAD HEKARL UZIR

Qualifications: B.Eng. (Leeds), M.Sc., DIC. (Imperial), Ph.D. (London)
Expertise: Biocatalysis, Biotransformation, Fermentation, Steady-State Analysis, Bifurcation Theory

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    1. Mohamad Hekarl Uzir, Nazalan Najimudin, (2018), On the bi-enzymatic behaviour of Saccharomyces cerevisiae-mediated stereoselective biotransformation of 2,6,6-trimethylcyclohex-2-ene-1,4-dione, Molecular Catalysis (formerly known as Journal of Molecular Catalysis A: Chemical), Vol. 447, 56-64.
    2. Lau S. Y., Fadzil N. G, Kamaruddin A. H. and Uzir M. H., (2013), Enzymatic Deracemization of (R,S)-Ibuprofen Ester via Lipase catalyzed Membrane Reactor, Industrial and Engineering Chemistry Research, No. 27, Vol. 52, 9441–9453.
    3. Fadzil Noor Gonawan, Lau Sie Yon, Azlina Harun Kamaruddin, Mohamad Hekarl Uzir, (2014), Rapid Base-Catalyzed Racemization of (R)-Ibuprofen Ester in 2 Isooctane−Dimethyl Sulfoxide Medium with Improved Kinetic Model, Industrial and Engineering Chemistry Research, No. 2, Vol. 53, 635-642.
    4. Khor Guat Kheng, Mohamad Hekarl Uzir, (2011), Saccharomyces cerevisiae as a Potential Stereospecific Reduction Tool for Biotransformation of Monoterpenoids. Yeast, No. 2, Vol. 28, 93–107.
    5. Aimi Aishah Ariffin, Mashitah Mat Don, Mohamad Hekarl Uzir, (2011), Baker's Yeast-Mediated Biotransformation of Geraniol into Citronellol Using a Continuous-Closed-Gas-Loop Bioreactor (CCGLB) System. Biochemical Engineering Journal. No. 1, Vol. 56, 219-224.
    1. Synthesizing precursor for tapentadol production through biotransformation.
    2. Investigating the effect of cofactor recycling in a bi-enzymatic bioconversion system.
    3. Designing new breed of bioreactor for biotransformation of fine chemicals for food and drugs industries.
    1. Modelling and Simulation of Membrane Bioreactor for S-Ibuprofen Production Pilot Plant.
    1. The Biotransformation of cis/trans 3,7-dimethyl-2,6-octadien-1-ol Mediated by Saccharomyces cerevisiae.
    2. The Effect of Different Solvent on the Downstream Process of S- Ibuprofen Production.
    3. Optimising the Production of Chiral Alcohol for Angiotensin Receptor Blocker (ARB) Synthesis via Aspergillus niger-Catalysed Biotransformation of 1-4-Bromo-phenyl-ethanone