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hekarl

ASSOCIATE PROFESSOR DR. MOHAMAD HEKARL UZIR

Qualifications: B.Eng. (Leeds), M.Sc., DIC. (Imperial), Ph.D. (London)
Expertise: Biocatalysis, Biotransformation, Fermentation, Steady-State Analysis, Bifurcation Theory

 

    1. Naim, M., Mohammat, M.F., Mohd Ariff, P.N.A., Uzir, M.H., (2024), Biocatalytic approach for the synthesis of chiral alcohols for the development of pharmaceutical intermediates and other industrial applications: A review, Enzyme and Microbial Technology, Vol. 180, No. 110483.
    2. Mohamad Hekarl Uzir, Nazalan Najimudin, (2018), On the bi-enzymatic behaviour of Saccharomyces cerevisiae-mediated stereoselective biotransformation of 2,6,6-trimethylcyclohex-2-ene-1,4-dione, Molecular Catalysis (formerly known as Journal of Molecular Catalysis A: Chemical), Vol. 447, 56-64.
    3. Fadzil Noor Gonawan, Lau Sie Yon, Azlina Harun Kamaruddin, Mohamad Hekarl Uzir, (2014), Rapid Base-Catalyzed Racemization of (R)-Ibuprofen Ester in 2 Isooctane−Dimethyl Sulfoxide Medium with Improved Kinetic Model, Industrial and Engineering Chemistry Research, No. 2, Vol. 53, 635-642.
    4. Khor Guat Kheng, Mohamad Hekarl Uzir, (2011), Saccharomyces cerevisiae as a Potential Stereospecific Reduction Tool for Biotransformation of Monoterpenoids. Yeast, No. 2, Vol. 28, 93–107.
    5. Aimi Aishah Ariffin, Mashitah Mat Don, Mohamad Hekarl Uzir, (2011), Baker's Yeast-Mediated Biotransformation of Geraniol into Citronellol Using a Continuous-Closed-Gas-Loop Bioreactor (CCGLB) System. Biochemical Engineering Journal. No. 1, Vol. 56, 219-224.
    1. Optimisation of bio-hydrogen production from cyanobacteria through recombinant DNA technique. (New – MSc. candidate required).
    2. Determining the mechanistic pathway of bi-enzymatic reductase enzymes during a biotransformation. (New – PhD. candidate required).
    1. Modelling and Simulation of Membrane Bioreactor for S-Ibuprofen Production Pilot Plant.
    2. Saccharomyces cerevisiae-mediated Biocatalytic Biotransformation of a Chloro-Aldehyde Forming a Chiral Precursor for Tapentadol Production.
    1. The Biotransformation of cis/trans 3,7-dimethyl-2,6-octadien-1-ol Mediated by Saccharomyces cerevisiae.
    2. The Effect of Different Solvent on the Downstream Process of S- Ibuprofen Production.
    3. Optimising the Production of Chiral Alcohol for Angiotensin Receptor Blocker (ARB) Synthesis via Aspergillus niger-Catalysed Biotransformation of 1-4-Bromo-phenyl-ethanone